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Injections are most frequently used for cosmetic procedures to help rejuvenate skin and reduce the appearance of wrinkles. They are also used for lip augmentation. In this office procedure, a filler is inserted into the treated area using a fine needle. In the case of fat injections, a needle is used first to remove fat from a donor site. The fat is then treated before it is inserted into the desired site, such as the lips. Patients are given anesthetics for the procedure based on patient tolerance and type or location of injectable used.